malignancy

Etymology

malignant +‎ -cy or malign +‎ -ancy

Noun

malignancy (countable and uncountable, plural malignancies)

1. The state of being malignant or diseased.
2. A malignant cancer; specifically, any neoplasm that is invasive or otherwise not benign.
3. That which is malign; evil, depravity, malevolence.
   • Shakespeare

     The malignancy of my fate might perhaps distemper yours.

   • 1902, Arthur Conan Doyle, The Hound of the Baskervilles‎:

     A cold wind swept down from it and set us shivering. Somewhere there, on that desolate plain, was lurking this fiendish man, hiding in a burrow like a wild beast, his heart full of malignancy against the whole race which had cast him out.