Fig. 44. — Thyroid gland — cystic goitre. The gland spaces vary in size and many may show marked cystic formation. These vesicles are filled with the colloid material (x 90 diam.)

Fig. 45. — Liver. Fatty Infiltration. The liver cells are seen to contain a large globule of fat which pushes the cell nucleus to one side— giving the signet-ring appearance. (x 250 diam.)

Fig. 50. — Phagocytic which have taken plasm particles of (X 500 diam.)

ellb (in sputum) into their protocarbon pigment.

Fig. 47. — Pudic artery showing calcified areas Fig. 46. — Heart. Fatty Infiltration. The fat in the muscular coat of the vessel. These cells are increased and infiltrate the con degenerated parts are darkly stained owing nective tissue between the bundles of to the calcareous particles having a strong muscle fibres. These are pressed upon and affinity for the haemotoxylin stain. (x 35 become atrophied, and may ultimately be diam.) replaced by adipose tissue. (x 40 diam.)

Fig. 49. — Melanotic sarcoma. Maiiyol ilnse malignant cells develop and accumulate in their protoplasm granules of melanin pigment. (x 300 diam.)

Fig. 48. — Brown atrophy of heart. The muscle fibres show the pigment granules, which are of a light yellow colour, situated specially at the poles of the fibre nucleus and extending short distance in the long axis of the fibre. (, -, 400 diam.)

Fig. 51. Liver, waxy. The swollen waxy capillaries are pressing on the columns of liver cells and are causing marked atrophy.

(.— 75 diam.)