For those not familiar with front running: it is the process of market/price manipulation. If I know, that a big purchase of s.th. valuable will happen, the amount of this would get more rare on the market and it's price may rise. Therefor I could quickly do my own purchase of such a good, speculating that the price will rise, and sell it after the big transaction at a higher price.

In the bitcoin world this is not excluded. Imagine that you are within a big financial corp, and this institute asks the trading desk to buy bitcoins for 10mio Euros. An employee could see this planned trade, and do a quick self trade before. So this is within corporations.

In the public bitcoin space, there is no indication of a "big" trade, that will happen on the blockchain. Usually a tx is composed and then sent into the network, to the nodes that you are linked with, and from there to the whole network. So if you could see this UTXO with an enourmous amount in your node, you have the time to create your own tx to do front running. It would need to get into a candidate block, before the "big" tx joins a block which is then minde. I do not see that there is a guarantee to do so. It might get different when a miner comes into the play, and he is hand crafting a tx, but I am not 100% sure... He would have to be fast enough, that no other miner has a candidate block, that get's into the blockchain before him...