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I'm interested in starting a gambling site, it has been difficult to find an easy way to handle user funds.
Solutions such as Bitpay or Coinbase disallow usage for gambling.
BIP32 blockchain notifiers like Mycelium Gear appear to be vulnerable to spam attacks and difficult to scale.
I've looked into interacting with a full node but things seem to get complicated very quickly at scale.
its a very general question. You can accept bitcoin by giving a qrcode of an address to user in your website and put a listener on that address through a simple API like blockchain.info (If you dont wanna run your full node) that gets triggered when the address gets a transaction. That's what bitpay does and it very simple – abeikverdi – 2016-08-18T08:11:46.740