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It is widely accepted that Bitcoin is both a transaction network, and a currency subject to speculative market action like established fiat currencies. In a sense, it is a transaction network with a 'capacitor' in the middle, which happens to be stored value in the form of the world's first distributed digital currency.
I investigated and performed some analysis around Bitcoin Days Destroyed, and found it a little empty in terms of measuring the adoption of Bitcoin as a tranactional currency. Instead, I simply took a moving average of the number of transactions per block as a straight indicator of real transactional activity. This analysis makes no attempt to measure or attribute meaning to the size of transactions; the focus is exclusively on the volume of transactions.
To that end, the attached is a graph of transactions per block which includes a linear best-fit trend and a 255 sample rolling average. Both show clearly that the transaction count has trended down over the past few months. How valid is this graph as a proxy for the adoption of Bitcoin as a tranactional currency, and what level of activity should we want to see before we'd consider Bitcoin a 'success' as such a currency?
NOTE: in the graph below, the the slope co-efficient is transactions/(block*day), so the implication is that the average number of transactions per block is falling at a rate of 0.0716 per day, or about 1 transaction fewer every 2 weeks.

The goal of the question was to zoom in on ordinary 'economic' transactions which are specifically not speculative in nature. The relatively high frequency FX transactions you mention are inherently of a speculative nature, so we should be able to ignore them for the purposes of this analysis. I am interested in a discussion about the adoption of Bitcoin as a currency for the purchase and sale of everyday things. – Andrew Jones – 2011-10-03T16:11:49.713
Except that we can't ignore certain kinds of transactions arbitrarily since there's no magical flag telling us what kind of transaction something was. MtGox accounts for a huge number of sent/received bitcoins every day. Even if they control the timing of their own sends in such a way that we could ignore them we have no idea how many transactions in a given block went TO MtGox and so we have no way of ignoring those transactions. There simply isn't a way at present to separate speculation-related transactions from actual commerce. – David Perry – 2011-10-03T16:39:46.370
Further to the existing comments, Bitcoins transactions going through exchanges are also useful for avoiding mainstream currency exchange fees. Even if it was possible to ignore exchange transactions, you'd be ignoring some genuinely useful transactions by doing so. eg http://sojyujai.org/2011/07/my-bitcoin-experiment/
– Highly Irregular – 2011-10-04T04:38:49.407