I'm attempting to use the createrawtransaction to manually create my transactions and I want to (obviously) reduce my fees. The complication I'm having is that I want to send ALL of the bitcoins in my wallet to 2 parties. So I know that I can specify the inputs and outputs, but there's that pesky fee concept which makes it difficult to just spend it all.

So if I have 5 inputs and 2 outputs, how would I go about calculating exactly what the fee will be and reducing it?