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Since the Standard Client version 0.8 removed the full index of all historical transactions, some Bitcoin applications that relied on that functionality have stopped working. For example, one is no longer able to find out the sender of a given transaction by pure RPC calls. How can one access that transaction detail in the newer versions of the Bitcoin client?
You cannot find the sender of a transaction in any case. You can find the addresses the input coins were previously sent to, but that is not necessarily the sender of the transaction, and not useful in general. – Pieter Wuille – 2013-06-29T13:38:18.277