P2Pool works differently from most mining systems - it aims to have a completed "mini-block" about every 10 seconds, so latency of the p2pool hosting server is critical - milliseconds count.

So it absolutely must be in a decent datacentre on a high-quality (aka not-cheap oversold contended junk) network, not on your home connection if you expect ever to get any mined income.

You'll also have to admin the server/os/software, apply patches and upgrades and generally maintain things which can be a full-time job.

I'd suggest you just join an existing one - find one "close" to your location - do a traceroute to it - the less hops and different networks the better.

The issue is latency between the p2pool network and the miner. Hosting your bitcoind instance in a datacenter will make little difference unless you move your mining too.